Radioimmunoassay of Mammalian Type C Viral Proteins

نویسندگان

  • Wade P. Parks
  • David M. Livingston
  • George J. Todaro
  • Raoul E. Benveniste
  • Edward M. Scolnick
چکیده

A radioimmunoassay specific for a murine leukemia virus structural protein, the gs antigen, detects an antigenic reactivity in normal murine cells in culture and natural tissues. The assay was shown to measure an antigen that is highly related to the virion protein as shown by absorption tests, immunoadsorbent chromatography, and by analysis of linearized dose-response curves. These findings combined with the finding of viral-specific RNA indicate that portions of the viral genome are being expressed with a much greater frequency than previously appreciated.

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عنوان ژورنال:
  • The Journal of Experimental Medicine

دوره 137  شماره 

صفحات  -

تاریخ انتشار 1973